diff --git a/README.md b/README.md
index b1c7852f..3393aa03 100644
--- a/README.md
+++ b/README.md
@@ -61,6 +61,7 @@ By default, the container will download the latest version of the "vanilla" [Min
       * [Modpack data directory](#modpack-data-directory)
       * [Buggy start scripts](#buggy-start-scripts)
       * [Fixing "unable to launch forgemodloader"](#fixing-unable-to-launch-forgemodloader)
+   * [Running a server with a packwiz modpack](#running-a-server-with-a-packwiz-modpack)
    * [Working with mods and plugins](#working-with-mods-and-plugins)
       * [Optional plugins, mods, and config attach points](#optional-plugins-mods-and-config-attach-points)
       * [Auto-downloading SpigotMC/Bukkit/PaperMC plugins](#auto-downloading-spigotmcbukkitpapermc-plugins)
@@ -660,6 +661,20 @@ then you apply a workaround by adding this to the run invocation:
 
     -e FTB_LEGACYJAVAFIXER=true
 
+## Running a server with a packwiz modpack
+
+[packwiz](https://packwiz.infra.link/) is a CLI tool for maintaining and providing modpack definitions, with support for both CurseForge and Modrinth as sources. See the [packwiz tutorial](https://packwiz.infra.link/tutorials/getting-started/) for more information.
+
+To configure server mods using a packwiz modpack, set the `PACKWIZ_URL` environment variable to the location of your `pack.toml` modpack definition:
+
+    docker run -d -v /path/on/host:/data -e TYPE=FABRIC \
+        -e "PACKWIZ_URL=https://example.com/modpack/pack.toml" \
+        itzg/minecraft-server
+
+packwiz modpack defitions are processed before other mod definitions (`MODPACK`, `MODS`, etc.) to allow for additional processing/overrides you may want to perform (in case of mods not available via Modrinth/CurseForge, or you do not maintain the pack).
+
+> packwiz is pre-configured to only download server mods. If client-side mods are downloaded and cause issues, check your pack.toml configuration, and make sure any client-only mods are not set to `"both"`, but rather `"client"` for the side configuration item.
+
 ## Working with mods and plugins
 
 ### Optional plugins, mods, and config attach points
diff --git a/scripts/start-setupModpack b/scripts/start-setupModpack
index 18605299..02036b46 100755
--- a/scripts/start-setupModpack
+++ b/scripts/start-setupModpack
@@ -20,6 +20,33 @@ if isTrue "${REMOVE_OLD_MODS}" && [ -z "${MODS_FILE}" ]; then
   removeOldMods /data/plugins
 fi
 
+# If packwiz url passed, bootstrap packwiz and update mods before other modpack processing
+if [[ "${PACKWIZ_URL}" ]]; then
+  # Ensure we have the latest packwiz bootstrap installer
+  latestPackwiz=$(curl -fsSL https://api.github.com/repos/comp500/packwiz-installer-bootstrap/releases/latest)
+  if [[ -z "${latestPackwiz}" ]]; then
+    log "WARNING: Could not retrieve Packwiz bootstrap installer release information"
+  else
+    isDebugging && log "Latest packwiz ${latestPackWiz}"
+    latestPackwizVer=$(echo ${latestPackwiz} | jq --raw-output '.tag_name')
+    latestPackwizUrl=$(echo ${latestPackwiz} | jq --raw-output '.assets[] | select(.name | match("packwiz-installer-bootstrap.jar")) | .url')
+    : "${PACKWIZ_JAR:=packwiz-installer-bootstrap_${latestPackwizVer}.jar}"
+    if [[ ! -e $PACKWIZ_JAR ]]; then
+      log "Downloading Packwiz ${latestPackwizVer}"
+      curl -H "Accept:application/octet-stream" -o "$PACKWIZ_JAR" -fsSL ${latestPackwizUrl}
+      ln -sf "${PACKWIZ_JAR}" packwiz-installer-bootstrap.jar
+    fi
+  fi
+  if [[ ! -e packwiz-installer-bootstrap.jar ]]; then
+    log "ERROR: Packwiz not available or could not be downloaded from Github!"
+    exit 1
+  fi
+  if isURL "${PACKWIZ_URL}"; then
+    log "Running packwiz against URL: ${PACKWIZ_URL}"
+    java -jar packwiz-installer-bootstrap.jar -g -s server "${PACKWIZ_URL}"
+  fi
+fi
+
 # If supplied with a URL for a modpack (simple zip of jars), download it and unpack
 if [[ "$MODPACK" ]]; then
   if isURL "${MODPACK}"; then